PHARMACY INFORMATION - DRUG INFORMATION - DISEASE STATES - PHARMACOLOGY - PHARMACEUTICS - DRUG THERAPY - MEDICINAL CHEMISTRY

PHARMACY INFORMATION RESOURCES
DISEASE STATE INFORMATION RESOURCES
DRUG INFORMATION RESOURCES

WE ARE THE TOP NICHE PHARMACY JOBS, NURSING JOBS, AND HEALTHCARE EMPLOYMENT SITES ON THE INTERNET!

PHARMACIST WEEK!

PHARMACY - DRUG - DISEASE STATE INFORMATION AND LINKS


PHARMACIST RESOURCE CENTER

TOP DRUGS DISPENSED IN US

1. HYDROCODONE BITARTRATE / ACETAMINOPHEN
2. TOPROL XL
3. SYNTHROID
4. NEXIUM
5. LIPITOR
TOP DRUG CLASSES DISPENSED IN US
1. CODEINE AND CODEINE ANALOG COMBINATIONS
2. SSRI/SNRI
3. STATINS
4. BETA BLOCKERS
5. ACE INHIBITORS
DRUGS IN THE NEWS
ROFECOXIB (VIOXX™)
VALDECOXIB (BEXTRA™)
MELOXICAM (MOBIC™)
CELECOXIB (CELEBREX™)
OXYCODONE HCL CONTROLLED RELEASE (OXYCONTIN™)
DISEASE STATES IN THE NEWS
MESOTHELIOMA AND ASBESTOSIS
SILICOSIS
ANTHRACOSIS AND BYSSINOSIS
ERECTILE DYSFUNCTION
BI-POLAR, MANIC, AND DEPRESSIVE DISORDERS
MELANOMAS AND SARCOMAS
NAME BRAND DRUGS AND MANUFACTURERS
ALL PHARMACEUTICAL MFGS A TO Z
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

BEXTRA (valdecoxib) - Pfizer

Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic and antipyretic properties in animal models. The mechanism of action is believed to be due to inhibition of prostaglandin synthesis primarily through inhibition of cyclooxygenase-2 (COX-2). At therapeutic plasma concentrations in humans valdecoxib does not inhibit cyclooxygenase-1 (COX-1).  Bextra was pulled from the US market in April of 2005 by request of the FDA.

.
 

 

BEXTRA NEWS AND INFORMATIONAL RESOURCES

TO ADVERTISE OR PLACE YOUR LINK HERE - CONTACT TPRICE @ GREATPHARMACYJOBS.COM

 

BEXTRA NEWS AND INFORMATION

Pfizer pulls Bextra from market
FDA asks Pfizer to put 'black box' warning on Celebrex

By Val Brickates Kennedy & Tomi Kilgore, MarketWatch
Last Update: 3:47 PM ET April 7, 2005  

BOSTON (MarketWatch) - At the request of the Food and Drug Administration, Pfizer Inc. agreed to remove its pain reliever Bextra from the market and to slap a sterner warning label on Celebrex, a sibling drug.

The FDA said it asked that Pfizer's Bextra be taken off the market because its medical benefits don't outweigh various risks that the drug poses. Likewise, the agency said that while Celebrex carries fewer risks, it should still carry a "black box" warning to advise users that it can cause cardiac problems in certain patients.

A "black box" warning is the sternest warning a medication can carry in the U.S. and still remain on the market.

Bextra already carried a black box warning advising it can cause a rare but potentially fatal skin condition caused Stevens-Johnson syndrome. It also carries another warning that it can cause serious cardiovascular problems in patients who have recently undergone cardiac surgery.

The FDA move is the latest chapter in the saga of whether a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs) can trigger cardiac problems in some long-term users. Bextra and Celebrex, along with Merck's withdrawn drug Vioxx, all belong to a sub-class of NSAIDs called Cox-2 inhibitors, which are believed to carry an even greater cardiac risk.

Long-term use of many NSAIDs has long been linked to stomach bleeding in some patients. Cox-2 inhibitors were once considered superior NSAIDs in that they could be taken long-term without running as much of a risk of gastrointestinal bleeding.

The FDA began to take a much harder look at the safety of NSAIDs and Cox-2 drugs after a clinical study linked Merck's Vioxx with an increased incidence of heart attack and stroke in certain patients.

As a result, the FDA held an advisory panel meeting in February on whether the medical benefits of NSAIDs and Cox-2 inhibitors outweighed their cardiovascular risks. At that time, the panel recommended, in a controversial series of votes, that Bextra, Celebrex and Merck's Vioxx be allowed to remain on the market.

"Today's actions protect and advance the health of the millions of Americans who rely on these drugs everyday," said Dr. Steven Galson, the acting director of the FDA's Center for Drug Evaluation and Research.

Pfizer said that while it disagrees with the FDA's position on Bextra's safety, it has agreed to suspend sales and marketing of the drug in the U.S. The company has also suspended Bextra sales in the European Union and is holding talks with regulators in other parts of the world.

Pfizer added that it plans to have further discussions with the FDA to determine if Bextra may be permitted back on the market for certain conditions. The company said that, in the meantime, it is advising Bextra users to stop taking the medication.

Meanwhile, analysts on Thursday said they believe Pfizer will have to revise its financial outlook further to reflect Bextra's removal from the market and a further erosion of Celebrex sales.

For 2004, Bextra had sales of $1.3 billion, while Celebrex took in $3.3 billion, according to Lehman Brothers.

Pfizer had just given new guidance on April 5 that lowered adjusted earnings estimates for 2005 to $2 a share. The company added that it expected adjusted earnings rebounding for 2005 and 2006, with growth being in the "double-digits." The company also proposed annual cost cuts of about $4 billion.

"The Bextra announcement comes as a surprise. Pfizer will have to lower guidance below $2," said Lehman analyst Anthony Butler on Thursday. "But they still can grow if they can do the cost cuts. Maybe they'll be more than $4 billion now."

"We view keeping Celebrex on the market as a success for Pfizer," wrote William Blair analyst Winton Gibbons. "We would now expect Pfizer to consider more substantive cost-cutting measures that may include reductions in headcount, specifically sales force, thus mitigating some of the revenue lost."

The FDA also said Thursday that it will "carefully review any proposal from Merck for resumption of marketing of Vioxx."

Merck said it hasn't yet decided whether it will put Vioxx back on the market, despite an FDA advisory panel's finding that the drug was still safe enough to be sold on the U.S. market, albeit with restrictions. The company added that it "looks forward" to meeting with the FDA to discuss the matter further.

The agency has also asked makers of NSAIDs, which include such popular pain relievers as ibuprofen and naproxen, to revise their labels to include a warning about possible cardiovascular risks.

"FDA is providing the public information based on the latest available scientific data to guide the careful and appropriate use of these drugs aimed at maximizing their potential benefits and minimizing their risks," the FDA's Galson said.

  

BEXTRA™ (valdecoxib) - PFIZER™  INFORMATION SEARCH BY LOCAL POPULATION CENTERS

1.New York, NY  Bextra™  (valdecoxib) - Pfizer -  Information and Resources
2. Los Angeles, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
3. Chicago, IL Bextra™  (valdecoxib) - Pfizer -  Information and Resources
4. Houston, TX Bextra™  (valdecoxib) - Pfizer -  Information and Resources
5. Philadelphia, PA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
6. Phoenix, AZ Bextra™  (valdecoxib) - Pfizer -  Information and Resources
7. San Diego, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
8. Dallas, TX Bextra™  (valdecoxib) - Pfizer -  Information and Resources
9. San Antonio, TX Bextra™  (valdecoxib) - Pfizer -  Information and Resources
10. Detroit, MI Bextra™  (valdecoxib) - Pfizer -  Information and Resources
11. San Jose, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
12. Indianapolis, IN Bextra™  (valdecoxib) - Pfizer -  Information and Resources
13. San Francisco, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
14. Jacksonville, FL Bextra™  (valdecoxib) - Pfizer -  Information and Resources
15. Columbus, OH Bextra™  (valdecoxib) - Pfizer -  Information and Resources
16. Austin, TX Bextra™  (valdecoxib) - Pfizer -  Information and Resources
17. Baltimore, MD Bextra™  (valdecoxib) - Pfizer -  Information and Resources
18. Memphis, TN Bextra™  (valdecoxib) - Pfizer -  Information and Resources
19. Milwaukee, WI Bextra™  (valdecoxib) - Pfizer -  Information and Resources
20. Boston, MA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
21. Washington, DC Bextra™  (valdecoxib) - Pfizer -  Information and Resources
22. Nashville, TN Bextra™  (valdecoxib) - Pfizer -  Information and Resources
23. El Paso, TX Bextra™  (valdecoxib) - Pfizer -  Information and Resources
24. Seattle, WA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
25. Denver, CO Bextra™  (valdecoxib) - Pfizer -  Information and Resources
26. Charlotte, NC Bextra™  (valdecoxib) - Pfizer -  Information and Resources
27. Fort Worth, TX Bextra™  (valdecoxib) - Pfizer -  Information and Resources
28. Portland, OR Bextra™  (valdecoxib) - Pfizer -  Information and Resources
29. Oklahoma City, OK Bextra™  (valdecoxib) - Pfizer -  Information and Resources
30. Tucson, AZ Bextra™  (valdecoxib) - Pfizer -  Information and Resources
31. New Orleans, LA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
32. Las Vegas, NV Bextra™  (valdecoxib) - Pfizer -  Information and Resources
33. Cleveland, OH Bextra™  (valdecoxib) - Pfizer -  Information and Resources
34. Long Beach, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
35. Albuquerque, NM Bextra™  (valdecoxib) - Pfizer -  Information and Resources
36. Kansas City, MO Bextra™  (valdecoxib) - Pfizer -  Information and Resources
37. Fresno, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
38. Virginia Beach, VA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
39. San Juan, PR Bextra™  (valdecoxib) - Pfizer -  Information and Resources
40. Atlanta, GA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
41. Sacramento, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
42. Oakland, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
43. Mesa, AZ Bextra™  (valdecoxib) - Pfizer -  Information and Resources
44. Tulsa, OK Bextra™  (valdecoxib) - Pfizer -  Information and Resources
45. Omaha, NE Bextra™  (valdecoxib) - Pfizer -  Information and Resources
46. Minneapolis, MN Bextra™  (valdecoxib) - Pfizer -  Information and Resources
47. Honolulu, HI Bextra™  (valdecoxib) - Pfizer -  Information and Resources
48. Miami, FL Bextra™  (valdecoxib) - Pfizer -  Information and Resources
49. Colorado Springs, CO Bextra™  (valdecoxib) - Pfizer -  Information and Resources
50. Saint Louis, MO Bextra™  (valdecoxib) - Pfizer -  Information and Resources
51. Wichita, KS Bextra™  (valdecoxib) - Pfizer -  Information and Resources
52. Santa Ana, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
53. Pittsburgh, PA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
54. Arlington, TX Bextra™  (valdecoxib) - Pfizer -  Information and Resources
55. Cincinnati, OH Bextra™  (valdecoxib) - Pfizer -  Information and Resources
56. Anaheim, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
57. Toledo, OH Bextra™  (valdecoxib) - Pfizer -  Information and Resources
58. Tampa, FL Bextra™  (valdecoxib) - Pfizer -  Information and Resources
59. Buffalo, NY Bextra™  (valdecoxib) - Pfizer -  Information and Resources
60. Saint Paul, MN Bextra™  (valdecoxib) - Pfizer -  Information and Resources
61. Corpus Christi, TX Bextra™  (valdecoxib) - Pfizer -  Information and Resources
62. Aurora, CO Bextra™  (valdecoxib) - Pfizer -  Information and Resources
63. Raleigh, NC Bextra™  (valdecoxib) - Pfizer -  Information and Resources
64. Newark, NJ Bextra™  (valdecoxib) - Pfizer -  Information and Resources
65. Lexington, KY Bextra™  (valdecoxib) - Pfizer -  Information and Resources
66. Anchorage, AK Bextra™  (valdecoxib) - Pfizer -  Information and Resources
67. Louisville Metro, KY Bextra™  (valdecoxib) - Pfizer -  Information and Resources
68. Riverside, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
69. Saint Petersburg, FL Bextra™  (valdecoxib) - Pfizer -  Information and Resources
70. Bakersfield, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
71. Stockton, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
72. Birmingham, AL Bextra™  (valdecoxib) - Pfizer -  Information and Resources
73. Jersey City, NJ Bextra™  (valdecoxib) - Pfizer -  Information and Resources
74. Norfolk, VA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
75. Baton Rouge, LA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
76. Hialeah, FL Bextra™  (valdecoxib) - Pfizer -  Information and Resources
77. Lincoln, NE Bextra™  (valdecoxib) - Pfizer -  Information and Resources
78. Greensboro, NC Bextra™  (valdecoxib) - Pfizer -  Information and Resources
79. Plano, TX Bextra™  (valdecoxib) - Pfizer -  Information and Resources
80. Rochester, NY Bextra™  (valdecoxib) - Pfizer -  Information and Resources
81. Glendale, AZ Bextra™  (valdecoxib) - Pfizer -  Information and Resources
82. Akron, OH Bextra™  (valdecoxib) - Pfizer -  Information and Resources
83. Garland, TX Bextra™  (valdecoxib) - Pfizer -  Information and Resources
84. Madison, WI Bextra™  (valdecoxib) - Pfizer -  Information and Resources
85. Fort Wayne, IN Bextra™  (valdecoxib) - Pfizer -  Information and Resources
86. Bayamon, Puerto Rico Bextra™  (valdecoxib) - Pfizer -  Information and Resources
87. Fremont, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
88. Scottsdale, AZ Bextra™  (valdecoxib) - Pfizer -  Information and Resources
89. Montgomery, AL Bextra™  (valdecoxib) - Pfizer -  Information and Resources
90. Shreveport, LA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
91. Augusta, GA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
92. Lubbock, TX Bextra™  (valdecoxib) - Pfizer -  Information and Resources
93. Chesapeake, VA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
94. Mobile, AL Bextra™  (valdecoxib) - Pfizer -  Information and Resources
95. Des Moines, IA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
96. Grand Rapids, MI Bextra™  (valdecoxib) - Pfizer -  Information and Resources
97. Richmond, VA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
98. Yonkers, NY Bextra™  (valdecoxib) - Pfizer -  Information and Resources
99. Spokane, WA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
100. Glendale, CA Bextra™  (valdecoxib) - Pfizer -  Information and Resources
 
 

 

PHARMACIST WANTED / HEALTHCARE ADVERTISING  |  FOR PHARMACISTS  | PHARMACY FAX  | FAQS  | INDEX  | NURSING JOBS | HOME


QUICK JUMP TO STATE PHARMACIST EMPLOYMENT

 AK  |  AL  |  AR AZ  |  CA  |  CO  |  CT  |  DC  |  DE  |  FL  |  GA  |  HI  |  ID  |  IA  |  IL  |  IN  |  KS  |  KY  |  LA  |  ME  |  MD  |  MA  |  MI  |  MN  |  MS  |  MO  |  MT  |  NE  |  NV  |  NH  |  NM  |  NJ NY  |  NC  |  ND  |  OH  |  OK  |  OR  |  PA  |  RI  |  SC SD  |  TN  |  TX  |  UTVT   |  VA  |  WA  |  WV  |  WI  |  WY  |  NATIONWIDE 

PHARMACIST SPECIALTIES
MAIL ORDER PHARMACY JOBS - RETAIL PHARMACY JOBS - NUCLEAR PHARMACY JOBS - CLINICAL PHARMACY JOBS - HOSPITAL PHARMACY JOBS - LONG TERM CARE (LTC) PHARMACY JOBS - DRUG REP JOBS - RX TECHNICIAN JOBS - HOME INFUSION PHARMACY JOBS - MANAGED CARE PHARMACY JOBS - DIRECTOR OF PHARMACY JOBS - NON-TRADITIONAL PHARMACY JOBS - CLOSED DOOR FACILITY PHARMACY JOBS - COMMUNITY OR INDEPENDENT PHARMACY JOBS - CLINIC PHARMACIST - CLINIC PHARMACIST MANAGER - COMPOUNDING PHARMACIST - HOME CARE PHARMACIST - HOSPICE PHARMACY JOBS - HOSPICE PHARMACIST MANAGER - HOSPITAL PHARMACY DIRECTOR - HOSPITAL PHARMACY MANAGER - IV PHARMACIST - LONG TERM CARE PHARMACIST - LONG TERM CARE PHARMACY MANAGER - MAIL ORDER PHARMACIST - NUCLEAR PHARMACIST - NUCLEAR PHARMACY MANAGER - ONCOLOGY PHARMACIST - PHARMACY DIRECTOR - PHARMACY MANAGER - PHARMACY TECHNICIANRESPIRATORY PHARMACIST - RESPIRATORY PHARMACY MANAGER - RETAIL PHARMACIST - RETAIL PHARMACY MANAGER - SPECIALTY PHARMACIST - SPECIALTY PHARMACY MANAGER - STAFF PHARMACY JOBS - STAFF PHARMACIST  - MBA PHARMACIST- NON-TRADITIONAL AND UNIQUE PHARMACY JOB OPPORTUNITIES, INCLUDING CORRECTIONAL FACULTY AND TRAVELING PHARMACY JOB OPPORTUNITIES - CLOSED DOOR FACILITY PHARMACY JOBS - COMMUNITY OR INDEPENDENT PHARMACY JOBS - DIET E-BOOK AND WEIGHT LOSS LINKS - PHARMACY GIFTS AND COLLECTABLES AT THE GPJ PHARMACY MARKETPLACE - AUBURN FOOTBALL - URGENT PHARMACY JOBS - PHARMACEUTICAL SALES TRAINING - DRUG REP JOBS - RESUMES AND INTERVIEW HELP - NURSING JOBS - DOSIMETRIST JOBS AND JOBS IN DOSIMETRY - ANESTHETIC NURSING AND NURSE ANESTHETIST - PHYSICAL THERAPIST REHAB THERAPY JOBS - FORENSIC PHARMACY JOBS - EMT PARAMEDIC JOBS -
INTERNET PHARMACY - PHARMACIST JOBS - SONOGRAPHY / ULTRASOUND JOBS - MEDICAL SCIENCE LIAISON JOBS - ONCOLOGY PHARMACY JOBS - ONCOLOGY PHARMACIST LINKS - CHAIN PHARMACY LINKS AND JOBS - INTERNATIONAL PHARMACISTS PHARMACY JOBS - RX PHARMACY RECRUITMENT - PHARMACY RECRUITERS

QUICK JUMP TO STATE NURSING EMPLOYMENT

AK | AL | AR | AZ | CA | CO | CT | DC | DE | FL | GA | HI | ID | IL | IN | IA | KS | KY | LA | ME | MD | MA | MI | MN | MS | MO | MT | NE | NV | NH | NM | NJ | NY | NC | ND | OH | OK | OR | PA | RI | SC | SD | TN | TX | UT | VT | VA | WA | WV | WI | WY | NATIONWIDE

 

 

Disclaimer - Please note - the positions that we have posted on this pharmacy job board are assumed to current and up-to-date.  However,  neither we, nor any of the organizations represented by this job board guarantee that a particular posted position will be open or available at any given time and assume no responsibility regarding such positions.  We do not accept any responsibility regarding outdated postings that may still be on the website, or the availability of those that are posted.  Please check with the advertiser for verification of job availability.

PHARMACIST WEEK SITE INDEX